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陳信宏 博士

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    聯絡人：唐維       資料來源：醫學研究科       聯絡資訊：twei@vghks.gov.tw       

    (A)期刊論文 for 2023 JCR

    1. Chen YC, Chang KT, Chen PM, Chen HH*. Silymarin Ameliorates Tacrolimus-induced Inflammation in Human Umbilical Vein Endothelial Cells. In Vivo. 2025 June 04; accepted. IF: 1.8; Ranking: 130/189, MEDICINE, RESEARCH & EXPERIMENTAL, 68.78% 通訊作者
    2. Chen HH, Kuo CT, Yang SH, Chang ST*, and Hu LH*. Dumbbell, Crescent and Tadpole shape Deformability of Erythrocytes on Intravascular Photobiomodulation via Micro-pillar array with Deep Learning visualizing. Chinese Journal of Physics. 2025 June; 95: 275-286. IF: 4.6; Ranking: 20/110, PHYSICS, MULTIDISCIPLINARY, 18.18% 第一作者
    3. Wu CJ, Li YH, Chen HH*. Exploring the Role of SGK1 in Kidney Physiology: Insights from Transcriptomic Analysis. BIOCELL. 2025 May 27; 49(5): 857-872. IF: 0.8; Ranking: 82/109, BIOLOGY, 75.23% 通訊作者
    4. Lan CW, Chen HH*, Sheu JJC*. Deoxyelephantopin induces apoptosis and cell cycle arrest in GL261 glioblastoma cells. Naunyn-Schmiedeberg's Archives of Pharmacology. 2025 Mar. 398(3): 2729-2738. IF: 3.1; SC: 126/354, PHARMACOLOGY & PHARMACY, 35.59% 共同通訊作者
    5. Chang CC, Li YH, Chang ST, and Chen HH*. Impact of Intravenous Laser Irradiation of Blood on Cognitive Function and Molecular Pathways in Long COVID Patients: A Pilot Study. QJM. 2025 Feb 17: hcaf050. IF: 7.3; Ranking: 22/325, MEDICINE, GENERAL & INTERNAL, 6.77% 通訊作者
    6. Chen YC, Chen CC, Chen RF, Chen HH*, Chen PM*. SPP1 mRNA Expression Is Associated with M2 Macrophage Infiltration and Poor Prognosis in Triple-Negative Breast Cancer. Current Issues in Molecular Biology. 2024; 46(12):13499-13513. IF: 2.8; Ranking: 184/313, BIOCHEMISTRY & MOLECULAR BIOLOGY, 58.78% 共同通訊作者
    7. Liu TH, Hsieh RJL, Chen HH, Kuo TJ, Lee JC, Lu WH*. Propranolol Alleviates Cardiac Injury After Acute Catecholamine Infusion via p38-MAPK Pathways. Journal of Cardiovascular Pharmacology, 2024 Jul 1;84(1):110-117. IF: 2.6; SC: 84/220, CARDIAC & CARDIOVASCULAR SYSTEMS, 38.18%
    8. Chen HH, Tang EK, Wu YJ, Wu FZ*. Impact of annual trend volume of low-dose computed tomography for lung cancer screening on overdiagnosis, overmanagement, and gender disparities. Cancer Imaging, 2024 June 12; 24 (1): 73. IF: 3.5; SC: 38/204, RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING, 18.63% 第一作者
    9. Wu CJ, Li YH, Wu FZ, Chen HH*. Eplerenone improves hyperglycemia and sympathetic excitation in chronic renocardiac syndrome in rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 2024 Feb;397(2):1081-1092. IF: 3.1; SC: 126/354, PHARMACOLOGY & PHARMACY, 35.59% 通訊作者
    10. Chen HH, Lin CY, Chen SJ, Huang WY, Kuo CW, Chang ST*. Intravascular laser irradiation of blood as novel migraine treatment: an observational study. European Journal of Medical Research, 2023 Oct 25;28(1):457. IF: 2.8; S/C: 92/189, MEDICINE, RESEARCH & EXPERIMENTAL, 48.68% 第一作者
    11. Wu CJ, Li YH, Chen HH*. Paricalcitol improved cardiac hypertrophy and fibrosis through upregulation of fibroblast growth factor 23 and downregulation of transforming growth factor-beta in a rat model of isoproterenol-induced cardiomyopathy. Chinese Journal of Physiology, 2023 Sep 18;66(5):306-312. IF: 1.4; SC: 73/85, PHYSIOLOGY, 85.88% 通訊作者
    12. Yen CC, Chen HH, Lee CH, Lin CH*. Predictive value of motor-evoked potentials for motor recovery in patients with hemiparesis secondary to acute ischemic stroke. Annals of Medicine. 2023 Jun 22; 55(1): 2225144. IF: 4.9, SC: 33/325, MEDICINE, GENERAL & INTERNAL, 10.15%
    13. Li YH, Sun CC, Chen PM, Chen HH*. SGK1 Target Genes Involved in Heart and Blood Vessel Functions in PC12 Cells. Cells. 2023 Jun 15; 12(12): 1641. IF: 5.1, SC: 63/205, CELL BIOLOGY, 30.73% 通訊作者
    14. Chu YT, Chen BH, Chen HH, Lee JC, Kuo TJ, Chiu HC, Lu WH. Hypoxia-Induced Kidney Injury in Newborn Rats. Toxics, 2023 Mar, 11(3), 260. IF: 3.9, SC: 23/106, TOXICOLOGY, 21.69%
    15. Pan JY, Lu WH, Wu CJ, Tseng CJ, Chen HH*. Prazosin Improves Neurogenic Acute Heart Failure through Downregulation of Fibroblast Growth Factor 23 in Rat Hearts. Chinese Journal of Physiology, 2022 Aug. 26; 65(4):179-86. IF: 1.4; SC: 73/85, PHYSIOLOGY, 85.88% 通訊作者
    16. Chen HH, Chern YB, Hsu CY, Tang PL, Lai CC*. Kidney transplantation waiting times and risk of cardiovascular events and mortality: a retrospective observational cohort study in Taiwan. BMJ Open, 2022 May 24;12(5): e058033. IF: 2.4; SC: 80/325, MEDICINE, GENERAL & INTERNAL, 23.61% 第一作者
    17. Tsai CK, Chen BH, Chen HH, Hsieh RJL, Lee JC, Chu YT, Lu WH*. Low-Dose Propranolol Prevents Functional Decline in Catecholamine-Induced Acute Heart Failure in Rats. Toxics. 2022; 10(5):238. IF: 3.9, SC: 23/106, TOXICOLOGY, 21.69%
    18. Yen CC#, Chen HH#, Hsu YT, Tseng CJ, Lin CH*. Effects of heavy metals in acute ischemic stroke patients: A cross-sectional study. Medicine, 2022 Mar 4;101(9): e28973. IF: 1.3; SC: 143/325, MEDICINE, GENERAL & INTERNAL, 44% 共同第一作者
    19. Wu CJ, Cheng PW, Kung MH, Ho CY, Pan JY, Tseng CJ, Chen HH*. Glut5 Knockdown in the Nucleus Tractus Solitarii Alleviates Fructose-Induced Hypertension in Rats. The Journal of Nutrition, 2022 Feb 8;152(2):448-457. IF: 3.7; SC: 37/114, NUTRITION & DIETETICS, 32.45% 通訊作者
    20. Lu WH, Chen HH, Chen BH, Lee JC, Lai CC, Li CH, Tseng CJ*. Norepinephrine Leads to More Cardiopulmonary Toxicities than Epinephrine by Catecholamine Overdose in Rats. Toxics, 2020 Sep 16; 8(3): 69. IF: 3.9, SC: 23/106, TOXICOLOGY, 21.69%
    21. Ho CY, Lin YT, Chen HH, HO WY, Sun GC, Hsiao M, Lu PJ, Cheng PW, Tseng CJ*. CX3CR1- microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats. Journal of Neuroinflammation, 2020 June 12; 17:185. IF: 9.3; SC: 17/310, Neurosciences, 5.48%
    22. Chen HH, Li YD, Cheng PW, Fang YC, Lai CC, Tseng CJ, Pan JY*, Yeh TC*. Gabapentin Reduces Blood Pressure and Heart Rate through the Nucleus Tractus Solitarii. Acta Cardiol Sin, 2019 Nov 14;35:627-633. IF: 1.8; SC: 128/220, CARDIAC & CARDIOVASCULAR SYSTEMS, 58.18% 第一作者
    23. Chen HH, Chu CH, Wen SW, Lai CC, Cheng PW, Tseng CJ*. Excessive Fructose Intake Impairs Baroreflex Sensitivity and Led to Elevated Blood Pressure in Rats. Nutrients, 2019 Oct 25;11(11): 2581. doi: 10.3390/nu11112581. IF: 4.8; SC: 18/114, NUTRITION & DIETETICS, 15.79% 第一作者
    24. Wu CJ, Chen HH, Cheng PW, Lu WH, Tseng CJ, Lai CC*. Outcome of robot assisted bilateral internal mammary artery grafting via left pleura in coronary bypass surgery. Journal of Clinical Medicine, 2019 Apr 12;8(4):502. IF: 3.0; R/C:58/325, MEDICINE, GENERAL & INTERNAL, 17.85%
    25. Lin CH, Yen CC, Hsu YT, Chen HH, Cheng PW, Tseng CJ, Lo YK, Chan JYH*. Baroreceptor Sensitivity Predicts Functional Outcome and Complications after Acute Ischemic Stroke. Journal of Clinical Medicine, 2019 Mar 3;8(3):300. IF: 3.0; R/C:58/325, MEDICINE, GENERAL & INTERNAL, 17.85%
    26. Chen HH, Yeh TC, Cheng PW, Ho WY, HO CY, Lai CC, Sun GC, Tseng CJ*. Antihypertensive potential of Coenzyme Q10 via free radical scavenging and enhanced Akt-nNOS signaling in the nucleus tractus solitarii in rats. Molecular Nutrition & Food Research, 2019 Mar; 63(6): e1801042. IF: 4.5; 42/173, FOOD SCIENCE & TECHNOLOGY, 24.28% 第一作者
    27. Lin YT, Wu YC, Sun GC, Ho CY, Wong TY, Lin CH, Chen HH, Yeh TC, Li CJ, Tseng CJ, Cheng PW*. Effect of Resveratrol on Reactive Oxygen Species-Induced Cognitive Impairment in Rats with Angiotensin II-Induced Early Alzheimer's Disease. Journal of Clinical Medicine, 2018 Oct 5;7(10). pii: E329. IF: 3.0; R/C:58/325, MEDICINE, GENERAL & INTERNAL, 17.85%
    28. Lin CH, Hsu YT, Yen CC, Chen HH, Tseng CJ, Lo YK, Chan JYH*. Association between heavy metal levels and acute ischemic stroke. Journal of Biomedical Science, 2018 May 25;25(1):49. IF: 9.0; R/C:15/189, MEDICINE, RESEARCH & EXPERIMENTAL, 7.94%

    (B)研討會論文:

    1. Chang ST, Chen IT, Chen HH. Efficacy and Mechanisms of Intravenous Laser Irradiation of Blood (ILIB) in Treating Brain Fog in Long COVID Patients. The 14th Across the Strait Scientific Conference on Cardiovascular Science and the 5th Conference of Asia-Pacific Undersea and Hyperbaric Medical Society 2024. Tainan, Taiwan. August 23-26, 2024.
    2. Yen CC, Lin CH, Chen IT, Chen HH. Predictive Value of Motor-Evoked Potentials for Functional Recovery in Acute Ischemic Stroke. The 14th Across the Strait Scientific Conference on Cardiovascular Science and the 5th Conference of Asia-Pacific Undersea and Hyperbaric Medical Society 2024. Tainan, Taiwan. August 23-26, 2024.
    3. Lin CH, Yen CC, Chen IT, Chen HH. PHGDH valine-altering variant is an important risk factor for stroke in the Taiwanese population. The 14th Across the Strait Scientific Conference on Cardiovascular Science and the 5th Conference of Asia-Pacific Undersea and Hyperbaric Medical Society 2024. Tainan, Taiwan. August 23-26, 2024.
    4. Chen HH, Jao TM, Li CJ, Chen JS. Impact of Irisin Deficiency on Podocytopathy and Diabetic Kidney Disease in a Murine Model. 2023 Annual Meeting of Taiwan Society of Nephrology, Taipei, Taiwan. Dec. 9-10, 2023.
    5. Chen HH, Li YH, Chen IZ. RNA-seq and differentially expressed gene analysis reveal the potential function of SGK1 in PC12 cells. The 19th World Congress of Basic and Clinical Pharmacology 2023. Glasgow, Scotland, United Kingdom. July 02~07, 2023.
    6. Chen HH, Chen IZ, Chang ST. Novel migraine treatment using intravascular laser irradiation of blood. The 19th World Congress of Basic and Clinical Pharmacology 2023. Glasgow, Scotland, United Kingdom. July 02~07, 2023

     

    (C)專利/獲獎:

    1. 陳信宏、張幸初、胡龍豪、郭清德 (2023)。中華民國專利號M647680。台北：經濟部智慧財產局。

    2. 台灣腎臟醫學年會論文口頭發表優秀論文獎, 2023

    3. 台灣創新技術博覽會發明競賽-銅獎, 2024

    4. 第20屆榮總台灣聯合大學合作研究論文獎, 2025

    5. 未來醫療AI點子大賽-第一名, 2025

    6. 未來醫療AI點子大賽-潛力新星獎, 2025

    7. 陳信宏、張幸初、胡龍豪、郭清德 (2025)。血球變形能力檢測晶片、使用其的方法及包含其的系統。發明專利已核准並辦理領證中(公開號202505196)。

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