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孔美蘭 博士

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    聯絡人：唐維       資料來源：醫學研究科       聯絡資訊：twei@vghks.gov.tw       
    1. Mei-Lang Kung, Siao Muk Cheng, Yun-Han Wang, Kai-Pi Cheng, Yi-Tsen Hsiao, Bertrand Chin-Ming Tan, and Yun-Wen Chen*. Deficiency of RNA adenosine deaminase (ADAR2) ameliorates metabolic-associated fatty liver disease via AMPK signaling pathways in male diet-induced obese mice. Communications Biology. 2024 May 17; 7(1):594. (SCI; 2022 IF=5.9)
    2. Mei-Lang Kung, Tai-Hua Yang, Chia-Chi Lin, Jia-Yun Ho, Tzu-Chi Hung, Chih-Hsiang Chang, Kuan-Wen Huang, Chien-Chin Chen, and Yun-Wen Chen*. ADAR2 deficiency ameliorates nonalcoholic fatty liver disease and muscle atrophy through modulating serum amyloid A1. Journal of Cachexia, Sarcopenia and Muscle. (27 Mar 2024 Accepted) DOI: 10.1002/jcsm.13460 (SCI; 2022 IF=8.9).
    3. Tsung-Hui Hu, Jian-Ching Wu, Shih-Tsung Huang, Tian-Huei Chu, Ting-Wei Shih, Yi-Chen Chang, Shih-Ming Yang, Pei-Chi Li, Chou-Yuan Ko, Kuo-Liang Huang, Mei-Lang Kung* and Ming-Hong Tai*. HDGF Stimulates Liver Tumorigenesis by Enhancing Reactive Oxygen Species Generation in Mitochondria. Journal of Biological Chemistry. 2023 Oct 10;299(11):105335. (SCI; 2022 IF=4.8).
    4. Mei-Lang Kung, Shih-Tsung Huang, Kuo-Wang Tsai, Tian-Huei Chu, and Shuchen Hsieh.* Nanosized zingerone-triggered anti-angiogenesis contributes to tumor suppression in human hepatocellular carcinoma. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 658: 130697, (2023). (SCI; 2022 IF=5.2)
    5. Tian-Huei Chu, Chou-Yuan Ko, Po-Han Tai, Yi-Chen Chang, Chao-Cheng Huang, Tung-Yang Wu, Hoi-Hung Chan, Ping-Hsuan Wu, Chien-Hui Weng, Yu-Wei Lin, Mei-Lang Kung, Cheng-Chieh Fang, Jian-Ching Wu, Zhi-Hong Wen, Yung-Kuo Lee, Tsung-Hui Hu,* Ming-Hong Tai.* Leukocyte cell-derived chemotaxin 2 regulates epithelial-mesenchymal transition and cancer stemness in hepatocellular carcinoma. Journal of Biological Chemistry 2022, (SCI; 2022 IF=4.8)
    6. Man-Gang Lee, Yung-Kuo Lee, Shih-Chung Huang, Chen-Lin Chang, Chou-Yuan Ko, Wen-Chin Lee , Tung-Yuan Chen, Shiow-Jyu Tzou, Cheng-Yi Huang, Ming-Hong Tai, Yu-Wei Lin, Mei-Lang Kung, Ming-Chao Tsai, Yung-Lung Chen, Yi-Chen Chang, Zhi-Hong Wen, Chao-Cheng Huang,* and Tian-Huei Chu.* DLK2 Acts as a Potential Prognostic Biomarker for Clear Cell Renal Cell Carcinoma Based on Bioinformatics Analysis. Genes 2022, 13(4), 629. (SCI; 2021 IF=3.5) (06 April 2022, Published.)
    7. Cheng-Mei Yang, Tian-Huei Chu, Kuo-Wang Tsai, Shuchen Hsieh, and Mei-Lang Kung*. Phytochemically Derived Zingerone Nanoparticles Inhibit Cell Proliferation, Invasion and Metastasis　in Human Oral Squamous Cell Carcinoma. Biomedicines 2022, 10(2), 320. (SCI; 2021 IF=4.757) (29 January 2022, Published.)
    8. Hui-Hwa Tseng, You-Zuo Chen, Nan-Hua Chou, Yen-Chih Chen, Chao-Chuan Wu, Li-Feng Liu, Yi-Fang Yang, Chung-Yu Yeh, Mei-Lang Kung, Ya-Ting Tu, Kuo-Wang Tsai*. Metformin inhibits gastric cancer cell proliferation by regulation of a novel Loc100506691-CHAC1 axis. Molecular Therapy: Oncolytics. (13 August 2021) (SCI; 2021 IF=6.311)
    9. Huey-Shan Hung, Kai-Bo Chang, Chang Ming Tang, Tian Ren Ku, Mei-Lang Kung, Alex Yang-Hao Yu, Chiung-Chyi Shen, Yi-Chin Yang, Hsien-Hsu Hsieh, Shan-hui Hsu*. Anti-inflammatory Fibronectin-AgNP for Regulation of Biological Performance and Endothelial Differentiation Ability of Mesenchymal Stem Cells. Int J Mol Sci. 2021 Aug 26; 22(17):9262. (SCI; 2021 IF=5.6)
    10. Huey-Shan Hung, Mei-Lang Kung, Yi-Chun Ke, Fang-Chung Chen, Chiung-Chyi Shen, Chang Ming Tang, Yi-Chin Yang, Chun-An Yeh, Hsien-Hsu Hsieh, Shan-hui Hsu*. Nanogold-Carried Graphene Oxide: Anti-inflammation and Increased Differentiation Capacity of Mesenchymal Stem Cells. Nanomaterials (07 August 2021. Accepted) (SCI; 2021 IF=5.719)
    11. Hui-Chen Chen, Mei-Lang Kung, Wei-Xiang Huang, Ru-Huei Fu, Alex Yang-Hao Yu, Ya-Tsu Yang, Huey-Shan Hung*. Delivery of Stromal-Derived Factor-1α via Biocompatible Gold Nanoparticles Promotes Dendritic Cells Viability and Migration. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 628: 127298, (2021). (30 July 2021. Accepted). (SCI; 2021 IF=5.2)
    12. Ruey-Hwang Chou, Meng-Yin Yang, Yi-Ping Yang, Chun-An Yeh, Wei-Yi Lai, Tzu-Wei Lin, Yuan-Chi Teng, Shu-Chen Hsieh, Mei-Lang Kung, Hsien-Hsu Hsieh, Huey-Shan Hung. Evaluating the Biocompatibility and Biological Performance of FePt-decorated Nano-epoxy Nanoparticles in Mesenchymal Stem Cells. Journal of the Chinese Medical Association (中華醫學雜誌). 2021 Oct 8. doi: 10.1097/JCMA.0000000000000627. (SCI; 2022 IF=3.0)
    13. Chiung-Chyi Shen, Meng-Yin Yang, Kai-Bo Chang, Chia-Hsuan Tseng, Yi-Ping Yang, Yi-Chin Yang, Mei-Lang Kung, Wei-Yi Lai, Tzu-Wei Lin, Hsien-Hsu Hsieh, Huey-Shan Hung*. Fabrication of Hyaluronic Acid-Gold Nanoparticles with Chitosan to Modulate Neural Differentiation of Mesenchymal Stem Cells. Journal of the Chinese Medical Association (中華醫學雜誌), (July 15 2021. Accepted). (SCI; 2022 IF=3.0)
    14. Yen-Ju Chiu, Ho-Hsiang Tu, Mei-Lang Kung, Hung-Ju Wu and Yun-Wen Chen.* Fluoxetine ameliorates high-fat diet-induced metabolic abnormalities partially via reduced adipose triglyceride lipase-mediated adipocyte lipolysis. Biomedicine & Pharmacotherapy. 41:111848, (2021). (SCI; 2022 IF=7.419)
    15. Kai-Bo Chang, Chiung-Chyi Shen, Shan-hui Hsu, Chang Ming Tang, Yi-Chin Yang, Sin-Ying Liu, Tian Ren Ku, Mei-Lang Kung, Hsien-Hsu Hsieh, and Huey-Shan Hung*. Functionalized collagen-silver nanocomposites for evaluation of the biocompatibility and vascular differentiation capacity of mesenchymal stem cells. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 624: 126814, (2021). (SCI; 2022 IF=5.2)
    16. Jui-Ho Wang, Tzung-Ju Lu, Mei-Lang Kung, Yi-Fang Yang, Chung-Yu Yeh, Ya-Ting Tu, Wei-Shone Chen, Kuo-Wang Tsai *. The Long Noncoding RNA LOC441461 (STX17-AS1) Modulates Colorectal Cancer Cell Growth and Motility. Cancers. 12: 3171 (2020) (SCI; 2022 IF=5.2)
    17. Chien-Hui Weng, Chieh-Shan Wu, Jian-Ching Wu, Mei-Lang Kung, Ming-Hsiu Wu*, Ming-Hong Tai*. Cisplatin-Induced Giant Cells Formation Is Involved in Chemoresistance of Melanoma Cells. International Journal of Molecular Sciences. 21(21): 7892 (2021). (SCI; 2022 IF=5.6)
    18. E‐Ming Wang, Tsung‐Hui Hu, Chao‐Cheng Huang, Yi‐Chen Chang, Shih‐Ming Yang, Shih‐Tsung Huang, Jian‐Ching Wu, Yi‐Ling Ma, Hoi‐Hung Chan, Li‐Feng Liu, Wen‐Bin Lu, Mei‐Lang Kung, Zhi‐Hong Wen, Jui‐Chu Wang, Chou‐Yuan Ko, Wei‐Lun Tsai, Tian‐Huei Chu*, Ming‐Hong Tai*. Hepatoma-derived Growth Factor Participates in Concanavalin A-induced Hepatitis. The FASEB Journal. 2020 Sep 28. doi: 10.1096/fj.202000511RR. (SCI; 2022 IF=4.8)
    19. Huey-Shan Hung*, Yang-Hao Yu, Shuchen Hsieh, Mei-Lang Kung, Hsiu-Yuan Huang, Ru-Huei Fu, Chun-An Yeh, Shan-Hui Hsu*, Enhanced biocompatibility and differentiation capacity of mesenchymal stem cells on polydimethylsiloxane by topographical patterned dopamine. ACS applied materials & interfaces. 12(40):44393-44406 (2020). (SCI; 2022 IF=9.5)
    20. Bi-Wen Yeh, Liang-En Yu, Ching-Chia Li, Juan-Cheng Yang, Wei-Ming Li, Yang-Chang Wu, Yu-Ching Wei, Hsueh-Te Lee, Mei-Lang Kung*, Wen-Jeng Wu*, The protoapigenone analog WYC0209 targets CD133+ cells: A potential adjuvant agent against cancer stem cells in urothelial cancer therapy. Toxicology and Applied Pharmacology, 402:115129 (2021). (SCI; 2022 IF=3.8)
    21. Huey-Shan Hung, Da-Tian Bau, Chun-An Yeh, Mei-Lang Kung*, Evaluation of cellular uptake mechanisms for AuNP-collagen-Avemar nanocarrier on transformed and non-transformed cell lines, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 580 (5):123791 (2019). (SCI; 2022 IF=5.2)
    22. Shuchen Hsieh*, I-Tin Li, Chiung-Wen Hsieh, Mei-Lang Kung, Shu-Ling Hsieh, Deng-Chyang Wu, Chao-Hung Kuo, Ming-Hong Tai, Huay-Min Wang, Wen-Jeng Wu, and Bi-Wen Yeh, Advances in Cellular Nanoscale Force Detection and Manipulation, Arabian Journal of Chemistry, 12: 3163- 3171 (2019). (SCI; 2022 IF=6.0)
    23. Tian-Huei Chu, Shih-Tsung Huang, Sheau-Fang Yang, Chia-Jung Li, Hong-Wei Lin, Bi-Chuang Weng, Shih-Ming Yang, Shih-Chung Huang, Jien-Ching Wu, Yi-Chen Chang, Zhi-Hong Wen, Yi-Ming Chen, Wen-Jeng Wu, Mei-Lang Kung, Po-Han Tai, and Deng-Chyang Wu and Ming-Hong Tai, Hepatoma-derived Growth Factor Participates in Helicobacter Pylori-induced Neutrophils Recruitment, Gastritis and Gastric Carcinogenesis, Oncogene, 38(37): 6461-6477 (2019). (SCI; 2022 IF=8.756)
    24. Mei-Lang Kung, P.Y. Lin, S.T. Huang, M.H. Tai, S.L. Hsieh, C.C. Wu, B.W. Yeh, W.J. Wu, S. Hsieh, Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines, ACS applied materials & interfaces 11(1): 137-150 (2019). (SCI; 2021 IF=9.5)
    25. C.C. Huang, S.H. Cheng, C.H. Wu, W.Y. Li, J.S. Wang, Mei-Lang Kung, T.H. Chu, S.T. Huang, C.T. Feng, S.C. Huang, M.H. Tai, Delta-like 1 homologue promotes tumorigenesis and epithelial-mesenchymal transition of ovarian high-grade serous carcinoma through activation of Notch signaling, Oncogene 38(17) (2019) 3201-3215. (SCI; 2021 IF=8.756)
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