Mitochondrial Communication and Signal Transduction The mitochondrion receives most recognition for its role in generating energy for cells in the body and they are commonly referred to as the powerhouse. Energy flow through our cells is largely driven by mitochondria, which in turn give us the ability to sense and perceive, integrate information, and adapt to stressors. Our research team combines knowledge from mitochondrial biology, reproductive endocrinology, aging, computational bioinformatics, and mitochondrial medicine to understand principles of mitochondrial communication and signal transduction. We deployed a mitochondrial phenotype analysis platform with our collaborators to map mitochondrial morphological differences and individual differences, understand mitochondrial plasticity over time, and map its role in human health and aging maintenance on various diseases.