高雄榮民總醫院教學研究部

學歷：

1. 國立中興大學生物醫學研究所博士班 (2009/09~2015/04)
2. 中國醫藥大學基礎醫學研究所碩士班 (2005/09~2007/06)

學術經歷：

1. 高雄榮民總醫院教學研究部契約高級助理研究員 (2020/03~迄今)
2. 台中榮民總醫院皮膚科博士後研究員 (2019/09~2019/12)
3. 中國醫藥大學中醫藥研究中心博士後研究員 (2017/08~2019/08)
4. 中國醫藥大學中醫系博士後研究員 (2016/08~2017/08)
5. 台中榮民總醫院風濕免疫科博士後研究員 (2016/05~2016/06)

1. 國立中興大學學術論文表現優秀獎 (2015/06、2016/04)
2. 第19屆國際東洋醫學學術大會壁報論文第一名

1. Member of the American Association of Immunologists (2017~迄今)

1. 小分子藥物調控免疫機制之探討
2. 屋塵螨誘發過敏性氣喘、過敏性鼻炎與小分子核醣核酸表現之探討
3. 中草藥於乾癬治療的免疫機轉之探討

1. EC Liao, JT Chen, ML Chao, SC Yu, CY Chang, WS Chu, , JJ Tsai. Nonadverse Effects on Allergenicity of Isopentenyltransferase-Transformed Broccoli. J Investig Allergol Clin Immunol 2013; 23: 112-119.
2. Sheng-Jie Yu, En-Chih Liao, Jaw-Ji Tsai. Der p 2 can induce bystander activation of B cells derived frompatients with systemic lupus erythematosus. Immunobiology 2014; 219: 958–963.
3. Sheng-Jie Yu, En-Chih Liao, Jaw-Ji Tsai. Effects of local nasal immunotherapy in allergic airwayinflammation: Using urea denatured Dermatophagoides pteronyssinus. Human Vaccines & Immunotherapeutics 2015; 11: 915-921.
4. Sheng-Jie Yu, En-Chih Liao, Meei-Ling Sheu, Dah-Tsyr Margaret Chang, Jaw-Ji Tsai. Cell-Penetrating Peptide Derived from Human Eosinophil Cationic Protein Inhibits Mite Allergen Der p 2 Induced Inflammasome Activation. PLoS ONE 2015; 10: e0121393.
5. En-Chih Liao, Ching-Yun Chang , Chia-Wei Hsieh , Sheng-Jie Yu , Sui-Chu Yin, Jaw-Ji Tsai. An Exploratory Pilot Study of Genetic Marker for IgE-Mediated Allergic Diseases with Expressions of FcεR1α and Cε. Int. J. Mol. Sci. 2015, 16, 9504-9519.
6. En-Chih Liao, Chia-Wei Hsieh, Ching-Yun Chang, Sheng-Jie Yu, Meei-Ling Sheu, Sheng-Mao Wu, Jaw-Ji Tsai. Enhanced Allergic Inflammation of Der p 2 Affected by Polymorphisms of MD-2 Promoter. Allergy Asthma Immunol Res. 2015 ;7:497-506.
7. Sheng-Jie Yu, En-Chih Liao, Jaw-Ji Tsai. House dust mite allergy: environment evaluation and disease prevention. Asia Pac Allergy 2014; 4: 241-252. Review
8. Sheng-Jie Yu, En-Chih Liao, Jaw-Ji Tsai. The stimulation of inflammasome activation and modulation of proinflammatory cytokine production by house dust mite major allergen in patients with SLE. Journal of Nature and Science 2015; 1:e126. Review
9. Fang-Liang Huang, Sheng-Jie Yu*. Esophageal cancer: Risk factors, genetic association and treatment. Asian Journal of Surgery 2018; 41: 210-215. Review

10. Fang-Liang Huang, En-Chih Liao, Sheng-Jie Yu*. House dust mite allergy: Its innate immune response and immunotherapy. Immunobiology 2018; 223: 300–302. Review
11. Fang-Liang Huang, Sheng-Jie Yu*. Predicting the therapeutic effect and incidence of multiple primary cancers in esophageal cancer patients. Asian Journal of Surgery 2018; 41, 521
12. Chia-Lin Lee*, Chien-Ming Wang, Hao-Chun Hu, Hung-Rong Yen, Ying-Chyi Song, Sheng-Jie Yu, Chao-Jung Chen, Wei-Chu Li, Yang-Chang Wu*. Indole alkaloids indigodoles A–C from aerial parts of Strobilanthes cusia in the traditional Chinese medicine Qing Dai have anti-IL-17 properties. PHYTOCHEMISTRY. 2019 Mar;162: 39-46
13. Ying-Chyi Song, Kuo-Feng Hung, Kai-Li Liang, Jen-Huai Chiang, Hui-Chi Huang, Li, Hui-Ju, Mei-Yao Wu, Sheng-Jie Yu, Hsin-Yi Lo, Tin-Yun Ho, Hung-Rong Yen*. Adjunctive Chinese herbal medicine therapy for nasopharyngeal carcinoma: Clinical evidence and experimental validation. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK. 2019 Sep;41(9):2860-2872
14. Cheng-Ying Shen, Chung-Yang Yen, Ding-Kuo Chien, Jaw-Ji Tsai, Sheng-Jie Yu, En-Chih Liao*. Influence of storage conditions on the infestation of Tyrophagus putrescentiae and prevalence of mite hypersensitivity in Taiwan. Experimental and Applied Acarology. 2020; 80: 381–398.
15. Kai-Li Liang, Sheng-Jie Yu, Wan-Chun Huang, Hung-Rong Yen*. Luteolin Attenuates Allergic Nasal Inflammation via Inhibition of Interleukin-4 in an Allergic Rhinitis Mouse Model and Peripheral Blood from Human Subjects with Allergic Rhinitis. Frontiers in Pharmacology, section Ethnopharmacology. Front. Pharmacol. 2020; 11:291-305.
16. Fang-Liang Huang, En-Chih Liao, Chia-Ling Li, Chung-Yang Yen*, Sheng-Jie Yu*. Pathogenesis of pediatric B-cell acute lymphoblastic leukemia: molecular pathways and disease treatments. Oncology Letters. ONCOLOGY LETTERS 2020; 20: 448-454. Review
17. Chung Yang Yen, Wen Dee Chiang, Shang Yong Liu, Sheng Jie Yu*, Ching Liang Hsieh*. Shikonin inhibits Der p 2 induced cytokine and chemokine expression in dendritic cells in patients with atopic dermatitis. Evidence-Based Complementary and Alternative Medicine 2020. In press.

1. House dust mite allergen induces inflammasome activation and NFkB signal B signal B signal B signal transduction in monocytes，Immunology 2017，華盛頓 D.C，2017.05/12~2017.05/16

2. IL-17 secreted by gd T cells could induce psoriasis and NFkB signal transduction in keratinocyte，生物醫學國際研討會暨第15屆前瞻生物醫學科學新知研討會，中國醫藥大學，2018.06/29~2018.06/30

3. 3H-1,2-dithiole-3-thione as a novel therapeutic agent for the treatment of imiquimod induced psoriasis-liked skin inflammation，2018 2nd CMU-HYU Joint Symposium，Taichung / Evergreen Laurel Hotel，2018.11/23~2018.11/23

4. Luteolin as a novel therapeutic agent for the treatment of allergic rhinitis，第19屆國際東洋醫學學術大會，Taipei / 台大國際會議中心，2018.11/24~2018.11/26

5. 3H-1,2-dithiole-3-thione as a Novel Therapeutic Agent for the Treatment of Imiquimod Induced Psoriasis-liked Skin Inflammation，The 2nd CMU-MU Joint Symposium，Taichung / Evergreen Laurel Hotel，2019.01/3 ~2019.01/4