高雄榮民總醫院內科部-部主任

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部主任

姓名	陳垚生
現職	高雄榮民總醫院內科部主任（2013.08~迄今）陽明大學醫學系臨床學科主任（2013.08~迄今）傳染病防治醫療網高屏區指揮官（2014~迄今）
學歷	高雄醫學大學醫務管理研究所碩士陽明醫大學醫學系醫學士
臨床經歷	高雄榮民總醫院內科部感染科主任高雄榮民總醫院病理檢驗部微生物科主任高雄榮民總醫院感染管制室主任高雄榮民總醫院內科部感染科主治醫師高雄榮民總醫院內科部感染科總醫師高雄榮民總醫院內科部住院醫師屏東龍泉榮民醫院內科住院醫師
學術經歷	陽明大學醫學系副教授美國愛荷華大學病理部抗感染研究中心研究員陽明大學醫學系醫學系助理教授中山大學生物醫學科學研究所合聘助理教授
專長	感染症學內科學微生物學院內感染控制
近年內曾參與之專題研究計畫	1.類鼻疽繼發多種器官膿瘍的傾向機制與發生風險之研究--CD11b訊息傳遞與調控B. pseudomallei細胞內寄生及組織間擴散之機制
	2.台灣感染症臨床試驗聯盟 III--共同主持人
	3.台灣感染症臨床試驗合作聯盟 II--共同主持人
	4.以 iNOS transgenic mice 研究小鼠感染廣東住血線蟲嗜伊紅性腦膜炎誘發ㄧ氧化氮與血腦屏障損傷之作用機轉--共同主持人
	5.胞內寄生類鼻疽誘發類鼻疽腦膜炎之木馬機制--共同主持人
	6.類鼻疽熱點區域污染B. pseudomallei的氣膠傳播與致病機制--主持人
	7.愛滋病個案管理及性病匿名篩檢計畫--主持人
	8.愛滋病個案管理師計畫--主持人
	9.台灣潛伏性結核感染疾病負載量以全血乙型干擾素方法進行評估--主持人
	10.以QuantiFERON-TB GOLD 方法進行結核病診斷之評估--主持人
	11.Brukholderia cepacia菌群之誘發發炎反應, 細胞毒性與動物感染之生物指標物分析--主持人
	12.dendritic cell 和廣東住血線蟲嗜伊紅性腦膜炎致病機轉--共同主持人
	13.社區與院內感染退伍軍人症之環境風險評估與醫院用水安全計畫評估--共同主持人
	14.伯克氏菌基因體之基因島(GI)及重覆性序列(TRS)與菌體感染之致病能力的相關性--共同主持人
	15.熱帶醫學整合型研究計畫--熱帶醫學核心計畫(2/3)--共同主持人
	16.蒜頭伯克氏菌群脂多醣體對樹突與巨噬細胞交互作用之研究--主持人
	17.以 iNOS transgenic mice 研究NO及其他發炎路徑在廣東住血線蟲引起之嗜伊紅性腦膜炎致病機轉--共同主持人
	18.整合型計畫-(子計畫二)急性與復發類鼻疽之細胞性免疫被Burkholderia pseudomallei關鍵因子所誘發--主持人
	19.MDR結核病醫療照護體系計畫--主持人
	20.增加登革出血熱流行嚴重度的機轉探究與防治策略--共同主持人
	21.臺灣人類腸病毒之分子流行病學調查(Molecular Epidemiology of Human enterovirus in Taiwan)--共同主持人
	22.蒜頭伯克氏菌活體脂多醣體之3-OH脂肪酸釋放量與其感染balb/c小鼠病理效應之關連性--共同主持人
	23.加強感染控制第二期-建置手部衛生示範中心--協同主持人
	24.性病免費匿名篩檢諮詢服務計畫--主持人
	25.Improvement in management of antibiotic treatment in acteremicpatients by infectious disease specialists(經感染症專家介入以促進菌血症患
近期發表著作	1. Chang, H. M., Tsai, H. C., Lee, S. S., Kunin, C., Lin, P. C., Wann, S. R., & Chen, Y. S. (2016). High daily doses of trimethoprim/sulfamethoxazole are an independent risk factor for adverse reactions in patients with pneumocystis pneumonia and AIDS. J Chin Med Assoc. doi: 10.1016/j.jcma.2016.01.007
	2. Chang, J. T., Yang, C. S., Chen, Y. S., Chen, B. C., Chiang, A. J., Chang, Y. H., . . . Chang, T. H. (2015). Genome and infection characteristics of human parechovirus type 1: the interplay between viral infection and type I interferon antiviral system. [Research Support, Non-U.S. Gov't]. PLoS One, 10(2), e0116158. doi: 10.1371/journal.pone.0116158
	3. Chen, J. K., Wu, K. S., Lee, S. S., Lin, H. S., Tsai, H. C., Li, C. H., . . . Chen, Y. S. (2016). Impact of implementation of the World Health Organization multimodal hand hygiene improvement strategy in a teaching hospital in Taiwan. Am J Infect Control, 44(2), 222-227. doi: 10.1016/j.ajic.2015.10.004
	4. Chen, P. S., Chen, Y. S., Lin, H. H., Liu, P. J., Ni, W. F., Hsueh, P. T., . . . Chen, Y. L. (2015). Airborne Transmission of Melioidosis to Humans from Environmental Aerosols Contaminated with B. pseudomallei. PLoS Negl Trop Dis, 9(6), e0003834. doi: 10.1371/journal.pntd.0003834
	5. Chen, W. L., Huang, I. F., Wang, J. L., Hung, C. H., Huang, J. S., Chen, Y. S., . . . Cheng, M. F. (2015). Comparison of acute lobar nephronia and acute pyelonephritis in children: a single-center clinical analysis in southern taiwan. [Research Support, Non-U.S. Gov't]. Pediatr Neonatol, 56(3), 176-182. doi: 10.1016/j.pedneo.2014.08.002
	6. Chen, Y. L., Chen, Y. S., Hung, Y. C., Liu, P. J., Tasi, H. Y., Ni, W. F., . . . Lin, H. H. (2015). Improvement in T helper 1-related immune responses in BALB/c mice immunized with an HIV-1 gag plasmid combined with a chimeric plasmid encoding interleukin-18 and flagellin. Microbiol Immunol, 59(8), 483-494. doi: 10.1111/1348-0421.12274
	7. Chen, Y. S., Lin, H. H., Hsueh, P. T., Liu, P. J., Ni, W. F., Chung, W. C., . . . Chen, Y. L. (2015). Whole-Genome Sequence of an Epidemic Strain of Burkholderia pseudomallei vgh07 in Taiwan. Genome Announc, 3(2). doi: 10.1128/genomeA.00345-15
	8. Chen, Y. Y., Chang, J. R., Kuo, S. C., Tseng, F. C., Huang, W. C., Huang, T. S., Chen, Y. S.,. . . Dou, H. Y. (2015). Molecular epidemiology of tuberculosis in Kaohsiung City located at southern Taiwan, 2000-2008. [Research Support, Non-U.S. Gov't]. PLoS One, 10(1), e0117061. doi: 10.1371/journal.pone.011706
	9. Cheng, M. F., Chen, W. L., Huang, I. F., Chen, J. R., Chiou, Y. H., Chen, Y. S., . . . Wang, J. L. (2016). Urinary tract infection in infants caused by extended-spectrum beta-lactamase-producing Escherichia coli: comparison between urban and rural hospitals. Pediatr Nephrol. doi: 10.1007/s00467-016-3338-0
	10. Cheng, M. F., Chen, W. L., Hung, W. Y., Huang, I. F., Chiou, Y. H., Chen, Y. S., . . . Wang, J. L. (2015). Emergence of Extended Spectrum-beta-Lactamase-Producing Escherichia coli O25b-ST131: A Major Community-Acquired Uropathogen in Infants. Pediatr Infect Dis J, 34(5), 469-475. doi: 10.1097/INF.0000000000000623
	11. Chiu, H. C., Hsieh, H. M., Lin, Y. C., Kuo, S. J., Kao, H. Y., Yeh, S. C., Chang, W. H., Hsiao, P. J., Chen, Y. S., . . . Wang, C. F. (2016). Patient assessment of diabetes care in a pay-for-performance program. Int J Qual Health Care, 28(2), 183-190. doi: 10.1093/intqhc/mzv120
	12. Chu, P. Y., Tyan, Y. C., Chen, Y. S., Chen, H. L., Lu, P. L., Chen, Y. H., . . . Motomura, K. (2015). Transmission and Demographic Dynamics of Coxsackievirus B1. PLoS One, 10(6), e0129272. doi: 10.1371/journal.pone.0129272
	13. Hsueh, P. T., Chen, Y. S., Lin, H. H., Liu, P. J., Ni, W. F., Liu, M. C., & Chen, Y. L. (2015). Comparison of Whole-Genome Sequences from Two Colony Morphovars of Burkholderia pseudomallei. Genome Announc, 3(5). doi: 10.1128/genomeA.01194-15
	14. Hsueh, P. T., Liu, J. K., Chen, Y. L., Liu, P. J., Ni, W. F., Chen, Y. S., . . . Lin, H. H. (2015). Genomic Sequence of Burkholderia multivorans NKI379, a Soil Bacterium That Inhibits the Growth of Burkholderia pseudomallei. Genome Announc, 3(6). doi: 10.1128/genomeA.01294-15
	15. Huang, H. W., Chen, Y. S., Chen, J. Y., Lu, P. L., Lin, Y. C., Chen, B. C., . . . Chu, P. Y. (2015). Phylodynamic reconstruction of the spatiotemporal transmission and demographic history of coxsackievirus B2. BMC Bioinformatics, 16(1), 302. doi: 10.1186/s12859-015-0738-2
	16. Hung, W. T., Lee, S. S., Sy, C. L., Wu, K. S., Chen, J. K., Tsai, H. C., & Chen, Y. S. (2015). Prevalence of latent tuberculosis infection in BCG-vaccinated healthcare workers by using an interferon-gamma release assay and the tuberculin skin test in an intermediate tuberculosis burden country. [Research Support, Non-U.S. Gov't]. J Microbiol Immunol Infect, 48(2), 147-152. doi: 10.1016/j.jmii.2013.07.008
	17. Jean, S. S., Lee, W. S., Bai, K. J., Lam, C., Hsu, C. W., Yu, K. W., Liao, C. H., Chang, F. Y., Ko, W. C., Wu, J. J., Chen, Y. H., Chen, Y. S., . . . Hsueh, P. R. (2015). Relationship between the distribution of cefepime minimum inhibitory concentrations and detection of extended-spectrum beta-lactamase production among clinically important Enterobacteriaceae isolates obtained from patients in intensive care units in Taiwan: results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) in 2007. [Multicenter Study Research Support, Non-U.S. Gov't]. J Microbiol Immunol Infect, 48(1), 85-91. doi: 10.1016/j.jmii.2013.07.002
	18. Jean, S. S., Lee, W. S., Bai, K. J., Yu, K. W., Hsu, C. W., Liao, C. H., Chang, F. Y., Ko, W. C., Wu, J. J.,Chen, Y. H., Chen, Y. S., . . . Hsueh, P. R. (2015). Carbapenem susceptibility among Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae isolates obtained from patients in intensive care units in Taiwan in 2005, 2007, and 2009. [Research Support, Non-U.S. Gov't]. Diagn Microbiol Infect Dis, 81(4), 290-295. doi: 10.1016/j.diagmicrobio.2014.09.027
	19. Jean, S. S., Lee, W. S., Yu, K. W., Liao, C. H., Hsu, C. W., Chang, F. Y., Ko, W. C., Chen, R. J., Wu, J. J., Chen, Y. H., Chen, Y. S., . . . Hsueh, P. R. (2015). Rates of susceptibility of carbapenems, ceftobiprole, and colistin against clinically important bacteria collected from intensive care units in 2007: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART). J Microbiol Immunol Infect. doi: 10.1016/j.jmii.2014.12.008
	20. Lee, C. Y., Tsai, H. C., Kunin, C. M., Lee, S. S., & Chen, Y. S. (2015). Clinical and microbiological characteristics of purulent and non-purulent cellulitis in hospitalized Taiwanese adults in the era of community-associated methicillin-resistant Staphylococcus aureus. BMC Infect Dis, 15, 311. doi: 10.1186/s12879-015-1064-z
	21. Lee, C. Y., Tsai, H. C., Lee, S., & Chen, Y. S. (2015). Orbital apex syndrome: an unusual complication of herpes zoster ophthalmicus. BMC Infect Dis, 15(1), 33. doi: 10.1186/s12879-015-0760-z
	22. Lee, C. Y., Tsai, H. C., Lee, S. S., Wu, K. S., Sy, C. L., Chen, J. K., & Chen, Y. S. (2015). Higher rate of hepatitis events in patients with human immunodeficiency virus, hepatitis B, and hepatitis D genotype II infection: A cohort study in a medical center in southern Taiwan. J Microbiol Immunol Infect, 48(1), 20-27. doi: 10.1016/j.jmii.2013.08.001
	23. Lee, S. S., Lin, H. H., Tsai, H. C., Su, I. J., Yang, C. H., Sun, H. Y., Hung, C. C., Sy, C. L., Wu, K. S., Chen, J. K., Chen, Y. S. & Fang, C. T.. (2015). A Clinical Algorithm to Identify HIV Patients at High Risk for Incident Active Tuberculosis: A Prospective 5-Year Cohort Study. PLoS One, 10(8), e0135801. doi: 10.1371/journal.pone.0135801
	24. Sy, C. L., Huang, T. S., Chen, C. S., Chen, Y. S., Tsai, H. C., Wann, S. R., . . . Liu, Y. C. (2016). Synergy of beta-Lactams with Vancomycin against Methicillin-Resistant Staphylococcus aureus: Correlation of Disk Diffusion and Checkerboard Methods. J Clin Microbiol, 54(3), 565-568. doi: 10.1128/JCM.01779-15
	25. Sy, C. L., Lee, S. S., Wu, K. S., Tsai, H. C., Liu, Y. C., & Chen, Y. S. (2016). Emergence of a strain of methicillin-resistant Staphylococcus aureus with decreased susceptibility to vancomycin 7 months after treatment with glycopeptide antibiotics. J Microbiol Immunol Infect, 49(1), 142-145. doi: 10.1016/j.jmii.2013.07.006
	26. Tsai, H. C., Chou, P. Y., Wann, S. R., Lee, S. S., & Chen, Y. S. (2015). Chemokine co-receptor usage in HIV-1-infected treatment-naive voluntary counselling and testing clients in Southern Taiwan. BMJ Open, 5(4), e007334. doi: 10.1136/bmjopen-2014-007334
	27. Tsai, H. C., Lee, B. Y., Yen, C. M., Wann, S. R., Lee, S. S., & Chen, Y. S. (2015). Dexamethasone inhibits brain apoptosis in mice with eosinophilic meningitis caused by Angiostrongylus cantonensis infection. Parasit Vectors, 8(1), 200. doi: 10.1186/s13071-015-0792-7
	28. Tsai, W. J., Lee, S. S., Tsai, H. C., Sy, C. L., Chen, J. K., Wu, K. S., . . . Chen, Y. S. (2016). Rapid onset of rhabdomyolysis after switching to a raltegravir-based antiretroviral regimen. J Microbiol Immunol Infect, 49(2), 286-288. doi: 10.1016/j.jmii.2013.02.008
	29. Tu, H. Z., Lin, Y. E., Tseng, M. R., Huang, T. S., & Chen, Y. S. (2015). Cost-effective identification of Mycobacterium tuberculosis complex using microscopic morphology and rapid tests. [Research Support, Non-U.S. Gov't]. Int J Tuberc Lung Dis, 19(10), 1204-1208. doi: 10.5588/ijtld.15.0781
	30. Wang, J. T., Chang, S. C., Chang, F. Y., Fung, C. P., Chuang, Y. C., Chen, Y. S., . . . Yang Lauderdale, T. L. (2015). Antimicrobial Non-Susceptibility of Escherichia coli from Outpatients and Patients Visiting Emergency Rooms in Taiwan. [Research Support, Non-U.S. Gov't]. PLoS One, 10(12), e0144103. doi: 10.1371/journal.pone.0144103
	31. Tseng YT, Tsai HC, Sy CL, Lee SS, Wann SR, Wang YH, Chen JK, Wu KS, Chen YS. Clinical manifestations of eosinophilic meningitis caused by Angiostrongylus cantonensis: 18 years' experience in a medical center in southern Taiwan. J Microbiol Immunol Infect. Epub 2011 Apr 29. Corresponder
	32. Tsai HC, Ye SY, Kunin CM, Lee SS, Wann SR, Tai MH, Shi MH, Liu YC, Chen YS. Expression of matrix metalloproteinases and their tissue inhibitors in the serum and cerebrospinal fluid of patients with HIV-1 infection and syphilis or neurosyphilis. Cytokine 2011;54(2):109-16. Corresponder
	33. Tsai HC, Shi MH, Lee SS, Wann SR, Tai MH, Chen YS. Expression of matrix metalloproteinases and their tissue inhibitors in the serum and cerebrospinal fluid of patients with meningitis. Clin Microbiol Infect 2011;17(5)780-4. Epub 2010 Dec 3. Corresponder
	34. Tsai HC, Lai PH, Sy CL, Lee SS, Yen CM, Wann SR, Chen YS. Encephalitis caused by Angiostrongylus cantonensis after eating raw frogs mixed with wine as a health supplement. Intern Med 2011;50(7): 771-4
	35. Liu YC, Lee SS, Chen YS, Tu HZ, Chen BC, Huang TS. Differential diagnosis of tuberculous and malignant pleurisy using pleural fluid adenosine deaminase and interferon gamma in Taiwan. J Microbiol Immunol Infect 2011;44(2): 88-94.
	36. Kao CH, Kuo YC, Chen CC, Chang YT, Chen YS, Wann SR, Liu YC. Isolated pathogens and clinical outcomes of adult bacteremia in the emergency department: a retrospective study in a tertiary Referral Center. J Microbiol Immunol Infect 2011;44(3): 215-21.
	37. Hsueh PR., Lau YJ, Ko WC, Liu CY, Huang CT, Yen MY, Liu YC, Lee WS, Liao CH, Peng MY, Chen CM, Chen YS. Consensus statement on the role of fluoroquinolones in the management of urinary tract infections. J Microbiol Immunol Infect 2011;44(2): 79-82.
	38. Tsai HC, Lee SS, Wann SR, Chen YS. Cervical lymphadenitis caused by Cryptococcus-related immune reconstitutional inflammatory syndrome." QJM 2010;103(7): 531-532.
	39. Sy CL, Lee SS, Liu MT, Tsai HC, Chen YS. Rapid emergence of oseltamivir resistance. Emerg Infect Dis 2010;16(4): 723-5. Corresponder
	40. Sheng WH, Liao CH, Lauderdale TL, Ko WC, Chen YS, Liu JW, Lau YJ, Wang LH, Liu KS, Tsai TY, Lin SY, Hsu MS, Hsu LY, Chang SC. A multicenter study of risk factors and outcome of hospitalized patients with infections due to carbapenem-resistant Acinetobacter baumannii. Int J Infect Dis 2010;14(9): e764-769.
	41. Liu YC, Lin HH, Chen YS, Su IJ, Huang TS, Tsai HC, Wann SR, Lee SS. Reduced health provider delay and tuberculosis mortality due to an improved hospital programme. Int J Tuberc Lung Dis 2010;14(1): 72-78.
	42. Liu PY, Huang YF, Tang CW, Chen YY, Hsieh KS, Ger LP, Chen YS, Liu YC. Staphylococcus lugdunensis infective endocarditis: a literature review and analysis of risk factors. J Microbiol Immunol Infect 2010;43(6): 478-484.
	43. Chu PY, Ke GM, Chen YS, Lu PL, Chen HL, Lee MS, Chen BC, Huang TS, Li YC, Chou LC, Wang SY, Lin KH. Molecular epidemiology of Coxsackievirus B3. Infect Genet Evol 2010;10(6): 777-784.
	44. Lee SS, Chou KJ, Dou HY, Huang TS, Ni YY, Fang HC, Tsai HC, Sy CL, Chen JK, Wu KS, Wang YH, Lin HH, Chen YS. High Prevalence of Latent Tuberculosis Infection in Dialysis Patients Using the Interferon-{gamma} Release Assay and Tuberculin Skin Test. Clin J Am Soc Nephrol 2010;5(8): 1451-7. Epub 2010 Jun 10. Corresponder
	45. Tu HZ, Chen YS, Lin YE, Tseng MR, Huang TS, Tsai HC, Liu YC. Combination of Molecular Assay and Clinical Evaluation for Early Confirmation of Tuberculosis Cases. Clin Microbiol Infect 2011;17(5): 712-4. Epub 2010 Jul 15
	46. Lin KH, Chen YS, Hu G, Tsay DG, Peng NJ. Chronic Bacterial Prostatitis Detected by FDG PET/CT in a Patient Presented With Fever of Unknown Origin. Clin Nucl Med 2010;35(11): 894-5.
	47. Young TG, Chen YS, Yen MY. Approach of Empirical Antibiotic Treatment: Analyzing Bacterial Resistance of Community-acquired Bacteremia. J Microbiol Immunol Infect. 2010 Feb;43(1):43-46. Epub 2010 Mar 29.
	48. Chen YS, Lin HH, Mu JJ, Chiang CS, Chen CH, Buu LM, Lin YE, Chen YL. Distribution of melioidosis cases and viable Burkholderia pseudomallei in soil: evidence for emerging melioidosis in Taiwan. J Clin Microbiol. 2010 Apr;48(4):1432-4. Epub 2010 Feb 10.
	49. Chen JK, Tsai HC, Liu YC, Wann SR, Wann SR, Lee SJ, Wang YH, Mai MH, Sy CL, Li YL, Chao PJ, Wu KS, Chen KM, Chen YS. Outbreak of Salmonella enteritidis B in a family in southern Taiwan. J Microbiol Immunol Infect. 2009 Dec;42(6):521-5. Corresponder
	50. Liu YC, Lin HH, Chen YS, Su IJ, Huang TS, Tsai HC, Wann SR, Lee SS. Reduced health provider delay and tuberculosis mortality due to an improved hospital programme. Int J Tuberc Lung Dis. 2010 Jan;14(1):72-8.
	51. Chen KM, Tsai HC, Sy CL, Lee SS, Liu YC, Wann SR, Wang YH, Mai MH, Chen JK, Wu KS, Chen YJ, Chen YS. Clinical manifestations of Japanese encephalitis in southern Taiwan. J Microbiol Immunol Infect. 2009 Aug;42(4):296-302. Corresponder.
	52. Tsai HC, Lee SS, Wann SR, Chen YS. Cervical lymphadenitis caused by Cryptococcus-related immune reconstitutional inflammatory syndrome. QJM 2010;103(7): 531-2. Epub 2009 Sep 23 . Corresponder
	53. Lee S S, Chou KJ, Su IJ, Chen YS, Fang HC, Huang TS, Tsai HC, Wann SR, Lin HH, Liu YC. High prevalence of latent tuberculosis infection in patients in end-stage renal disease on hemodialysis: Comparison of QuantiFERON-TB GOLD, ELISPOT, and tuberculin skin test. Infection 2009;37(2): 96-102.
	54. Lee SS, Ke CM, Cheng MF, Chen JH, Lin LJ, Hung MN, Chao HL, Li CH, Lu HH, Huang YH, Chen YJ, Sy CL, Wu KS, Chen JK, Tsai HC, Chen YS. Nosocomial Transmission of Undetected, Imported Measles in Taiwan, 2008. Infect Control Hosp Epidemiol. 2009 Oct;30(10):1026-8. Corresponder
	55. Chen BC, Cheng MF, Huang TS, Liu YC, Tang CW, Chen CS, Chen YS. Detection and identification of human parechoviruses from clinical specimens. Diagn Microbiol Infect Dis. 2009;65(3): 254-60. Epub 2009 Sep 1. Corresponder
	56. Tsai HC, Huang YL, Kiu YC, Wann SR, Lee SS, Chen ER, Yen CM, TaiMH, Shi MH, Chen YS. Dynamic changes of hepatocyte growth factor in eosinophilic meningitis caused by Angiostrongylus cantonensis infection. Am J Trop Med Hyg. 2009 Jun;80(6):980-2. Corresponder
	57. Chen YS, Lin HH, Hung CC, Mu JJ, Hsiao YS, Chen YL. Phenotypic characteristics and pathogenic ability across distinct morphotypes of Burkholderia pseudomallei DT. Microbiol Immunol. 2009 Mar;53(3):184-9.
	58. Chen YS, Lin HH, Wu CH, Hsiao YS, Hsu NS, Chen YL. Colonization of a medical center in Southern Taiwan by epidemic strains of carbapenem- and multidrug-resistant Acinetobacter baumannii and the genetic organization of their integrons. Jpn J Infect Dis. 2009 Mar;62(2):155-7.
	59. Wu KS, Tsai HC, Lee SS, Liu YC, Wann SR, Wang YH, Mai MH, Chen JK, Sy CL, Chen KM, Chen YJ, Chen YS. Comparison of clinical characteristics of amebic liver abscess in human immunodeficiency virus (HIV)-infected and non-HIV-infected patients. J Microbiol Immunol Infect. 2008 Dec;41(6):456-61. Corresponder
	60. Lee SS, Chou KJ, Su IJ, Chen YS, Fang HC, Huang TS, Tsai HC, Wann SR, Lin HH, Liu YC. High prevalence of latent tuberculosis infection in patients in end-stage renal disease on hemodialysis: Comparison of QuantiFERON-TB GOLD, ELISPOT, and tuberculin skin test. Infection. 2009 Apr;37(2):96-102. Epub 2008 Dec 10.
	61. Sy CL, Tsai HC, Wann SR, Lee SS, Liu YC, Chen YS. Cerebrospinal fluid hepatocyte growth factor level in meningitis. J Microbiol Immunol Infect. 2008 Aug;41(4):301-6. Corresponder
	62. Tsai HC, Chao PJ, Sy CL, Lee SS, Chen YS, Wann SR, Liu YC. Community-associated methicillin-resistant Staphylococcus aureus infective endocarditis with Panton-Valentine leukocidin gene in an injection drug user with HIV infection. Intern Med. 2008;47(16):1485-9. Epub 2008 Aug 15.
	63. Lee SS, Chen YS, Tsai HC, Wann SR, Lin HH, Huang CK, Liu YC. Predictors of septic metastatic infection and mortality among patients with Klebsiella pneumoniae liver abscess. Clin Infect Dis. 2008 Sep 1;47(5):642-50.
	64. Tsai HC, Liu SF, Wu KS, Liu YC, Shi MH, Chen ER, Yen CM, Lee SS, Huang YL, Chen YS. Dynamic changes of matrix metalloproteinase-9 in patients with Klebsiella pneumoniae meningitis. Inflammation. 2008 Aug;31(4):247-53.
65. Tsai HC, Chung LY, Chen ER, Liu YC, Lee SS, Chen YS, Sy CL, Wann SR, Yen CM. Association of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinase-4 in cerebrospinal fluid with blood-brain barrier dysfunction in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis. The American journal of tropical medicine and hygiene 2008, 78(1):20-27.
66. Tsai HC, Chao PJ, Sy CL, Lee SS, Chen YS, Wann SR, Liu YC. Community-associated methicillin-resistant Staphylococcus aureus infective endocarditis with panton-valentine leukocidin gene in an injection drug user with HIV infection. Intern Med. 2008;47(16):1485-9. Epub 2008 Aug 15
67. Sy CL, Tsai HC, Wann SR, Lee SS, Liu YC, Chen YS. Cerebrospinal fluid hepatocyte growth factor level in meningitis. J Microbiol Immunol Infect. 2008 Aug;41(4):301-30. Coresponder
68. Li WK, Chen YS, Wann SR, Liu YC, Tsai HC. Lactococcus garvieae endocarditis with initial presentation of acute cerebral infarction in a healthy immunocompetent man. Intern Med. 2008;47(12):1143-6. Epub 2008 Jun 16.
69. Lee SS, Chen YS, Tsai HC, Wann SR, Lin HH, Huang CK, Liu YC. Predictors of septic metastatic infection and mortality among patients with Klebsiella pneumoniae liver abscess. Clin Infect Dis. 2008 Sep 1;47(5):642-50.
70. Lee SS, Liu YC, Huang TS, Chen YS, Tsai HC, Wann SR, Lin HH: Comparison of the interferon- gamma release assay and the tuberculin skin test for contact investigation of tuberculosis in BCG-vaccinated health care workers. Scandinavian journal of infectious diseases 2008, 40(5):373-380.
71. Tsai HC, Chung LY, Chen ER, Liu YC, Lee SS, Chen YS, Sy CL, Wann SR, Yen CM: Association of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinase-4 in cerebrospinal fluid with blood-brain barrier dysfunction in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis. The American journal of tropical medicine and hygiene 2008, 78(1):20-27.
72. Huang TS, Liu YC, Sy CL, Chen YS, Tu HZ, Chen BC: In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis complex isolated in Taiwan over 10 years. Antimicrobial agents and chemotherapy 2008, 52(6):2226-2227.
73. Hsu CC, Lin YE, Chen YS, Liu YC, Muder RR. Validation study of artificial neural network models for prediction of methicillin-resistant Staphylococcus aureus carriage. Infect Control Hosp Epidemiol. 2008 Jul;29(7):607-14.
74. Huang TS, Lee SS, Hsueh PR, Tsai HC, Chen YS, Wann SR, Leu HS, Ko WC, Yan JJ, Yuan SZ et al: Antimicrobial resistance of rapidly growing mycobacteria in western Taiwan: SMART program 2002. J Formos Med Assoc 2008;107(4): 281-7.
75. Liu JY, Lin HH, Liu YC, Lee SS, Chen YL, Hung CC, Ko WC, Huang CK, Lai CH, Chen YS, Shih YL, Chung HC, Liang SH, Lin JN. Extremely high prevalence and genetic diversity of hepatitis C virus infection among HIV-infected injection drug users in Taiwan. Clin Infect Dis 2008; Jun 1;46(11):1761-8.
76. Huang TS, Liu YC, Bair CH, Sy CL, Chen YS, Tu HZ, Chen BC: Detection of M. tuberculosis using DNA chips combined with an image analysis system. Int J Tuberc Lung Dis 2008, 12(1):33-38. IF:2.035; 31/47
77. Chen YS, Lin YE, Liu YC, Huang WK, Shih HY, Wann SR, Lee SS, Tsai HC, Li CH, Chao HL et al: Efficacy of point-of-entry copper--silver ionisation system in eradicating Legionella pneumophila in a tropical tertiary care hospital: implications for hospitals contaminated with Legionella in both hot and cold water. The Journal of hospital infection 2008, 68(2):152-158.
78. Yu PY, Lin YE, Lin WR, Shih HY, Chuang YC, Ben RJ, Huang WK, Chen YS, Liu YC, Chang FY, Yen MY, Liu CC, Ko WC, Lin HH, Shi ZY. The high prevalence of Legionella pneumophila contamination in hospital potable water systems in Taiwan: implications for hospital infection control in Asia. Int J Infect Dis [2008 Feb 1;Epub ahead of print] IF:2.062; 29/47
79. Tsai HC, Chung LY, Chen ER, Liu YC, Lee SS, Chen YS, Sy CL, Wann SR, Yen CM. Association of matrix metalloproteinase-9 and tissue inhibitors of metalloproteinase-4 in cerebrospinal fluid with blood-brain barrier dysfunction in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis. Am J Trop Med Hyg. 2008 Jan;78(1):20-7. IF:2.546; 3/11

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