:::
Cephalosporins (IV)
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Cefazolin |
Bone and joint infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Infective endocarditis |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Bacteremia |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Empirical use |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Pulmonary infection |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Intra-abdominal infection |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Skin and soft tissue infection |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Urinary tract infection |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Surgical prophylaxis |
1 gm
IV stat
|
1 gm
IV stat
|
1 gm
IV stat
|
1 gm
IV stat
|
1 gm
IV stat
|
1 gm
IV stat
|
1 gm
IV stat
|
1 gm
IV stat
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Cephalexin |
Bone and joint infection |
2 gm
IV q6h
|
2 gm
IV q6h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
500mg
IV q8h
|
500mg
IV qd
|
500mg
IV qpm
|
| |
Bacteremia |
1 gm
IV q6h
|
1 gm
IV q6h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
500mg
IV q8h
|
500mg
IV qd
|
500mg
IV qpm
|
| |
Empirical use |
1 gm
IV q6h
|
1 gm
IV q6h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
500mg
IV q8h
|
500mg
IV qd
|
500mg
IV qpm
|
| |
Pulmonary infection |
1 gm
IV q6h
|
1 gm
IV q6h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
500mg
IV q8h
|
500mg
IV qd
|
500mg
IV qpm
|
| |
Urinary tract infection |
1 gm
IV q6h
|
1 gm
IV q6h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
500mg
IV q8h
|
500mg
IV qd
|
500mg
IV qpm
|
| |
Intra-abdominal infection |
1 gm
IV q6h
|
1 gm
IV q6h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
500mg
IV q8h
|
500mg
IV qd
|
500mg
IV qpm
|
| |
Infective endocarditis |
1 gm
IV q6h
|
1 gm
IV q6h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
500mg
IV q8h
|
500mg
IV qd
|
500mg
IV qpm
|
| |
Skin and soft tissue infection |
1 gm
IV q6h
|
1 gm
IV q6h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
500mg
IV q8h
|
500mg
IV qd
|
500mg
IV qpm
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Cefuroxime |
Bone and joint infection |
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q12h
|
1.5 gm
IV qd
|
1.5 gm
IV qpm
|
| |
Bacteremia |
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q12h
|
1.5 gm
IV q12h
|
1.5 gm
IV qd
|
1.5 gm
IV qpm
|
| |
Empirical use |
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q12h
|
1.5 gm
IV q12h
|
1.5 gm
IV qd
|
1.5 gm
IV qpm
|
| |
Pulmonary infection |
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q12h
|
1.5 gm
IV q12h
|
1.5 gm
IV qd
|
1.5 gm
IV qpm
|
| |
Urinary tract infection |
0.75gm
IV q8h
|
0.75gm
IV q8h
|
0.75gm
IV q8h
|
0.75gm
IV q8h
|
0.75gm
IV q12h
|
0.75gm
IV q12h
|
0.75gm
IV qd
|
0.75gm
IV qpm
|
| |
Intra-abdominal infection |
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q12h
|
1.5 gm
IV q12h
|
1.5 gm
IV qd
|
1.5 gm
IV qpm
|
| |
Skin and soft tissue infection |
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q8h
|
1.5 gm
IV q12h
|
1.5 gm
IV q12h
|
1.5 gm
IV qd
|
1.5 gm
IV qpm
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Cefoxitin |
Bone and joint infection |
2 gm
IV q6h
|
2 gm
IV q6h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Surgical prophylaxis |
2 gm
IV stat
|
2 gm
IV stat
|
2 gm
IV stat
|
2 gm
IV stat
|
2 gm
IV stat
|
2 gm
IV stat
|
2 gm
IV stat
|
2 gm
IV stat
|
| |
Bacteremia |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Empirical use |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Pulmonary infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Pulmonary NTM infection |
2 gm
IV q6h
|
2 gm
IV q6h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Urinary tract infection |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Intra-abdominal infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Skin and soft tissue infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Cefotaxime |
Bone and joint infection |
2 gm
IV q6h
|
2 gm
IV q6h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Bacteremia |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Empirical use |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Pulmonary infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Urinary tract infection |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Prostatitis |
2 gm
IV q6h
|
2 gm
IV q6h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Intra-abdominal infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Central nervous system infection |
2 gm
IV q6h
|
2 gm
IV q6h
|
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Skin and soft tissue infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qpm
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Ceftriaxone |
Bone and joint infection |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Bacteremia |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Empirical use |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Pulmonary infection |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Urinary tract infection |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Prostatitis |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Intra-abdominal infection |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Central nervous system infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qpm
|
| |
Skin and soft tissue infection |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
| |
Infectious diarrhea |
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qpm
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Ceftazidime |
Bone and joint infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qod
|
2 gm
IV tiw
|
| |
Sepsis |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qod
|
2 gm
IV tiw
|
| |
Bacteremia |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV QPM
|
| |
Septic shock |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV QPM
|
| |
Empirical use |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qod
|
2 gm
IV tiw
|
| |
Pulmonary infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qod
|
2 gm
IV tiw
|
| |
Urinary tract infection |
1 gm
IV q8h
|
1 gm
IV q8h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qod
|
1 gm
IV tiw
|
| |
Intra-abdominal infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qod
|
2 gm
IV tiw
|
| |
Central nervous system infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qod
|
2 gm
IV tiw
|
| |
Skin and soft tissue infection |
2 gm
IV q8h
|
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
2 gm
IV qod
|
2 gm
IV tiw
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Cefepime |
Bone and joint infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Sepsis |
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Bacteremia |
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Septic shock |
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Empirical use |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Empirical use for neutropenic fever |
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Pulmonary infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Urinary tract infection |
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
0.5 gm
IV qd
|
0.5 gm
IV qpm
|
| |
Intra-abdominal infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Central nervous system infection |
2 gm
IV q8h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Skin and soft tissue infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV qd
|
2 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Cefoperazone/sulbactam |
Bone and joint infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Sepsis |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Bacteremia |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Septic shock |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Empirical use |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Empirical use for neutropenic fever |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Pulmonary infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Urinary tract infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Intra-abdominal infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Central nervous system infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
| |
Skin and soft tissue infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Cefpirome |
Bone and joint infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Sepsis |
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Bacteremia |
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Septic shock |
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Empirical use |
1 gm
IV q12h
|
1 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV qd
|
0.5 gm
IV qd
|
0.5 gm
IV qpm
|
| |
Empirical use for neutropenic fever |
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Pulmonary infection |
1 gm
IV q12h
|
1 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV qd
|
0.5 gm
IV qd
|
0.5 gm
IV qpm
|
| |
Urinary tract infection |
1 gm
IV q12h
|
1 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Intra-abdominal infection |
1 gm
IV q12h
|
1 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV qd
|
0.5 gm
IV qd
|
0.5 gm
IV qpm
|
| |
Central nervous system infection |
2 gm
IV q12h
|
2 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV q12h
|
1 gm
IV qd
|
1 gm
IV qd
|
1 gm
IV qpm
|
| |
Skin and soft tissue infection |
1 gm
IV q12h
|
1 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV q12h
|
0.5 gm
IV qd
|
0.5 gm
IV qd
|
0.5 gm
IV qpm
|
TOP↑
| Antibiotics |
Indications |
Ccr
≧60
|
Ccr
50-59
|
Ccr
40-49
|
Ccr
30-39
|
Ccr
20-29
|
Ccr
10-19
|
Ccr
<10
|
HD |
| Ceftaroline |
Sepsis/Septic shock |
600 mg
IV q12h
|
600 mg
IV q12h
|
400 mg
IV q12h
|
400 mg
IV q12h
|
300 mg
IV q12h
|
300 mg
IV q12h
|
200 mg
IV q12h
|
200 mg
IV q12h
|
| |
Bacteremia |
600 mg
IV q12h
|
600 mg
IV q12h
|
400 mg
IV q12h
|
400 mg
IV q12h
|
300 mg
IV q12h
|
300 mg
IV q12h
|
200 mg
IV q12h
|
200 mg
IV q12h
|
| |
Empirical use |
600 mg
IV q12h
|
600 mg
IV q12h
|
400 mg
IV q12h
|
400 mg
IV q12h
|
300 mg
IV q12h
|
300 mg
IV q12h
|
200 mg
IV q12h
|
200 mg
IV q12h
|
| |
Pulmonary infection |
600 mg
IV q12h
|
600 mg
IV q12h
|
400 mg
IV q12h
|
400 mg
IV q12h
|
300 mg
IV q12h
|
300 mg
IV q12h
|
200 mg
IV q12h
|
200 mg
IV q12h
|
| |
Skin and soft tissue infection |
600 mg
IV q12h
|
600 mg
IV q12h
|
400 mg
IV q12h
|
400 mg
IV q12h
|
300 mg
IV q12h
|
300 mg
IV q12h
|
200 mg
IV q12h
|
200 mg
IV q12h
|
TOP↑
附註：所提供資訊不能取代醫師之治療及醫師與病患之關係